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. 2022 Jun 8;12:910792. doi: 10.3389/fonc.2022.910792

Table 2.

Median and interquartile range (Q1, Q3) plan parameters of the replanned doses based on manual (MAN), and autosegmented contours using precision (asPREC) and MIM (asMIM) vs. non-adapted planned doses (NoAd).

Structure Parameters No adaptation (NoAd) Replanning
MAN_Rp – NoAd ρ asPREC_Rp – NoAd ρ asMIM_Rp – NoAd ρ
PTV Coverage (%) 83.8 (78.0, 90.7) -2.0 (-4.6, 0.1) <.001 -2.7 (-4.5, -0.6) <.001 -5.1 (-8.4, -2.6) <.001
Dmean (Gy) 43.1 (42.2, 44.1) -0.5 (-1.0, 0.0) <.001 -0.3 (-0.7, 0.0) <.001 -0.7 (-1.2, -0.1) <.001
Dmin (Gy) 26.7 (25.5, 28.2) -0.5 (-1.6, 0.3) <.001 -0.7 (-1.4, 0.1) <.001 -0.5 (-1.5, 0.2) <.001
GTV Coverage (%) 95.7 (91.1, 99.0) -0.1 (-2.1, 0.6) 0.02 -0.4 (-1.9, 0.1) <.001 -1.6 (-5.2, 0.0) <.001
Dmean (Gy) 45.8 (45.0, 46.5) -0.5 (-1.0, 0.0) <.001 -0.1 (-0.7, 0.2) <.001 -0.5 (-1.2, 0.1) <.001
Stomach V35 Gy (cc) 0.2 (0.0, 0.8) -0.2 (-0.8, 0.0) <.001 -0.1 (-0.7, 0.0) <.001 -0.1 (-0.4, 0.0) <.001
Dmean (Gy) 5.4 (3.3, 7.4) -0.1 (-0.5, 0.5) NS -0.0 (-0.5, 0.5) NS -0.1 (-0.5, 0.4) NS
Duodenum V35 Gy (cc) 0.5 (0.1, 1.2) -0.4 (-1.0, 0.0) <.001 -0.2 (-0.7, 0.0) <.001 -0.2 (-0.5, 0.0) <.001
Dmean (Gy) 9.7 (5.7, 12.7) -0.3 (-1.1, 0.3) <.001 -0.4 (-1.0, -0.1) <.001 -0.4 (-0.9, 0.1) <.001
Bowel V35 Gy (cc) 0.0 (0.0, 0.3) 0.0 (-0.3, 0.0) <.001 0.0 (-0.1, 0.0) <.001 0.0 (-0.1, 0.0) <.001
Dmean (Gy) 1.9 (1.3, 2.6) -0.1 (-0.3, 0.1) <.001 -0.2 (-0.3, 0.0) <.001 -0.2 (-0.3, 0.0) <.001

Statistically not significant (NS) for p > 0.05.