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. 2022 Jun 8;12:910792. doi: 10.3389/fonc.2022.910792

Table 4.

Median and interquartile range (Q1, Q3) of the volumetric difference of auto and manual contours in fractions violating and non-violating dose-constraints (V35Gy > 0.5cc) in the stomach, duodenum and bowel after replanning using precision (asPREC) and MIM (asMIM) autocontours.

Structure Method Distance to PTV VOL_DIFF (AUTO – MAN) [cc]
Do not violate(V35 < 0.5 cc) Violate(V35 > 0.5 cc) ρ
Stomach asPREC Ring 0 – 1.5 cm 0.3 (-1.6, 2.0) -10.9 (-13.6, -3.1) .002
Ring 1.5 – 3 cm -1.9 (-7.2, 2.3) -17.9 (-25.6, 3.4) NS
asMIM Ring 0 – 1.5 cm 1.7 (-0.0, 6.2) -6.2 (-10.2, 1.1) <.001
Ring 1.5 – 3 cm 1.0 (-4.2, 4.6) -1.0 (-11.7, 8.1) NS
Duodenum asPREC Ring 0 – 1.5 cm 0.2 (-2.3, 2.8) -2.9 (-6.1, -1.1) .001
Ring 1.5 – 3 cm -0.1 (-5.6, 1.7) 0.2 (-2.2, 4.8) NS
asMIM Ring 0 – 1.5 cm 0.5 (-2.2, 2.7) -3.0 (-7.4, 0.5) .007
Ring 1.5 – 3 cm -0.4 (-7.1, 2.1) 0.3 (-6.7, 2.3) NS
Bowel asPREC Ring 0 – 1.5 cm 0.5 (-1.5, 6.4) -7.8 (-11.9, -4.9) <.001
Ring 1.5 – 3 cm 0.5 (-10.7, 8.2) -6.0 (-10.1, -2.8) NS
asMIM Ring 0 – 1.5 cm 1.0 (-0.8, 12.0) -6.2 (-6.6, -3.4) .017
Ring 1.5 – 3 cm 6.6 (-3.7, 27.9) 2.5 (1.3, 4.5) NS

Results are presented for the contour evaluated in the ring from 0 to 1.5 cm from the PTV vs. the ring from 1.5 to 3 cm from the PTV. Statistically not significant (NS) for p > 0.05.