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Summary of mutations to used mimic surface charge modifications in PyMol.
| Charge variant | Modification chemistry | Target residues | PyMol mutations |
|---|---|---|---|
| Unmodified | N/A | N/A | N/A |
| Acetylated |
|
Primary Amines (Lys)> | Lys → Ala |
| Neutralized |
|
Carboxylic Acid (Asp or Glu)> | Asp → Ala |
| Glu → Ala | |||
| Succinylated |
|
Primary Amines (Lys)> | Lys → Asp |
| Cationized |
|
Carboxylic Acid (Asp or Glu)> | Asp → Lys |
| Glu → Lys |
