TABLE 3.
Up and downregulated lncRNAs and proximity to putative stroke genes.
| Probe name | lncRNA ID | Cyto-band | Gene in region | lncRNA Up-/down-stream | lncRNA Distance (kb) from gene | FC |
|---|---|---|---|---|---|---|
| ASHGV40004037 | NR_046612 | 13q14.2 | HTR2A | within | within | 8.7159 |
| ASHGV40013775 | NR_002312 | 14q11.2 | PARP2 | down | 45 | 6.1135 |
| ASHGV40056557 | NR_037932 | 19q13.32 | APOC2 | down | 416.9 | 4.7449 |
| APOC4 | down | 419.2 | ||||
| APOE | down | 461.9 | ||||
| ASHGV40056142 | T111838 | 14q32.33 | MTA1 | within | within | 4.6273 |
| ASHGV40042838 | T294865 | 5q35.3 | ADAMTS2 | up | 346.4 | 4.0617 |
| ASHGV40043041 | T297706 | 6p23 | SIRT5 | down | 5.7 | 3.9144 |
| ASHGV40008778 | ENST00000530525 | 11q13.3 | ANO1 | within | within | −14.6300 |
| ASHGV40001758 | ENST00000395996 | 8q22.2 | VPS13B | within | within | −14.0950 |
| ASHGV40037155 | NR_045414 | 4p16.3 | HTT | down | 7.6 | −6.3636 |
| ASHGV40053990 | ENST00000416061 | XP11.23 | SUV39H1 | down | 3.4 | −4.9941 |
Significant DE lncRNA probe sets in stroke vs. non-stroke groups and their proximity to putative stroke genes (“-” means downregulated, fold change (FC) ≥ 2.0, p < 0.05).