Table 3.
Overview of reasons for a BICLA non-response/SRI(4) response at week 52 in TULIP-1 among BICLA non-responders/SRI(4) responders
BICLA non-response/SRI response, n (%) | SRI(4) responders/BICLA non-responders in TULIP-1 | |
Placebo (n=28) |
Anifrolumab 300 mg (n=12) |
|
BICLA non-response due to rash/ SRI response due to arthritis |
20 (71.4) | 5 (41.7) |
BICLA non-response due to rash/ SRI response not due to arthritis |
4 (14.3) | 3 (25.0) |
BICLA non-response on arthritis/ SRI response due to any reason |
2 (7.1) | 2 (16.7) |
Other* BICLA non-response/ SRI response due to any reason |
2 (7.1) | 2 (16.7) |
*Non-response due to a clinical manifestation other than rash or arthritis.
BICLA, British Isles Lupus Assessment Group-based Composite Lupus Assessment; SRI(4), Systemic Lupus Erythematosus Responder Index of ≥4.