Table 5.
Multivariate Cox regression analysis of OS and PFS.
| Variables | OS | PFS | ||||
|---|---|---|---|---|---|---|
| HR | 95% CI | P-value | HR | 95% CI | P-value | |
| Age (years) | ||||||
| <60 ≥60 |
Reference 1.749 |
1.028-2.978 | 0.039 | |||
| Smoke | ||||||
| No Yes |
Reference 1.106 |
0.618-1.980 | 0.735 | |||
| KPS | ||||||
| 90-100 70-80 |
Reference 1.515 |
0.848-2.706 | 0.161 | Reference 1.263 |
0.746-2.139 | 0.385 |
| Patient histology | ||||||
| SCC AD |
Reference 4.217 |
1.657-10.736 | 0.003 | |||
| PLR | ||||||
| ≤91.50 >91.50 |
Reference 1.209 |
0.654-2.237 | 0.545 | Reference 0.556 |
0.242-1.273 | 0.165 |
| C-SII score | ||||||
| 0 1-2 |
Reference 1.749 |
1.176-2.601 | 0.006 | Reference 2.472 |
1.624-3.763 | <0.001 |
BM, brain metastases; HR, hazard ratio; CI, confidence interval; OS, overall survival; PFS, progression-free survival; Cho, choline; Cr, creatine; NAA, N-acetyl-aspartate.