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. 2022 Jun 8;13:896628. doi: 10.3389/fphar.2022.896628

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Copyright © 2022 Ren, Zhang, Tao, Chen, Zou, Guo, Shen, Feng and Hu.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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The effects of a single dose of GJ-IFM (100 mg/kg) in CUMS mice on SPT and body weight. (A) SPT after 3 weeks of CUMS administration. t-test, ^* p < 0.05; control vs. CUMS + vehicle. (B) Body weight after 3 weeks of CUMS administration. t-test, ^** p < 0.01, ^*** p < 0.001; control vs. CUMS + vehicle. (C) The effects of a single dose of GJ-IFM (100 mg/kg) treatment in CUMS mice on SPT at 1 d. One-way ANOVA, ^*** p < 0.001; control vs. CUMS + vehicle; ^## p < 0.01; CUMS + vehicle vs. CUMS + GJ-IFM. (D) The effects of a single dose of GJ-IFM (100 mg/kg) treatment in CUMS mice on SPT on 10 d. One-way ANOVA, ^*** p < 0.001, control vs. CUMS + vehicle; ^### p < 0.001, CUMS + vehicle vs. CUMS + GJ-IFM.