. 2022 Jun 8;10:896253. doi: 10.3389/fchem.2022.896253

TABLE 2.

Mean concentrations (M) and corresponding standard deviations (SD) of metabolites contained in cinnamon extracts dissolved in CD₃OD as determined from ¹H-NMR spectra. Concentrations of metabolites are expressed in mg/g of extract. M and SD of the extraction yields are also reported. Results are reported as the mean and SD of three independent experiments.

	CZE		CZHE		CZH		CCE		CCHE		CCH		BCE		BCHE		BCH
	M	SD	M	SD	M	SD	M	SD	M	SD	M	SD	M	SD	M	SD	M	SD
Acetate	8.23	1.25	0.92	0.42	1.57	0.99	2.04	0.22	0.14	0.09	0.68	0.17	2.53	0.99	3.50	0.54	5.92	2.25
Benzoic acid	0.54	0.53	0.70	0.21	0.07	0.10	2.43	0.90	1.39	0.93	0.74	0.81	1.91	1.32	0.65	0.84	0.55	0.41
2,3-Butanediol	2.64	0.31	ND	ND	0.91	0.40	ND	ND	ND	ND	ND	ND	ND	ND	ND	0.21	ND	ND
β-Caryophyllene	27.25	9.01	3.55	2.51	3.98	1.94	14.53	2.49	2.09	1.55	3.11	0.77	28.29	8.70	12.65	3.23	8.02	0.33
Choline	1.05	0.66	1.64	0.46	1.68	0.53	0.46	0.52	1.91	0.17	2.63	0.44	1.42	0.50	2.31	0.80	2.79	0.07
(E)-Cinnamaldehyde	156.65	38.98	9.72	6.59	57.24	21.76	151.31	15.53	33.86	19.54	59.15	9.47	130.93	7.09	49.31	15.29	29.96	8.41
Cinnamaldehyde dimethyl acetal	42.26	10.93	ND	ND	ND	ND	10.36	5.04	3.11	2.23	4.39	1.13	14.26	1.78	ND	ND	3.42	1.70
Cinnamic acid	11.35	5.70	7.12	4.76	4.77	2.31	3.11	2.17	6.47	2.02	4.72	2.43	6.75	5.60	11.24	4.85	10.62	2.27
(Z)-Cinnamaldehyde	2.09	1.48	1.56	2.21	0.81	0.51	0.70	0.44	3.30	2.53	0.54	0.19	0.94	0.21	0.61	0.26	1.51	0.96
Coumarin	0.96	0.68	0.65	0.53	0.63	0.90	ND	ND	ND	ND	ND	ND	ND	ND	ND	ND	ND	ND
Eugenol	14.23	0.70	7.92	0.80	7.65	2.13	ND	ND	ND	ND	ND	ND	ND	ND	ND	ND	ND	ND
Formate	ND	ND	0.93	1.04	0.46	0.45	ND	ND	3.59	1.37	1.06	1.15	1.11	1.31	0.52	0.21	0.59	0.28
Galactose	ND	ND	ND	ND	ND	ND	ND	ND	ND	ND	10.66	3.23	16.62	6.03	ND	ND	22.98	3.61
Glucose	57.97	32.30	27.36	15.77	28.86	8.55	65.78	19.52	68.86	6.93	74.74	20.77	93.96	21.97	72.62	21.11	88.96	1.94
Glycerol	ND	ND	ND	ND	4.44	6.28	19.71	9.14	12.73	0.44	15.84	3.65	9.83	4.79	10.40	5.00	16.99	0.14
2-Hydroxycinnamaldehyde	3.50	2.27	ND	ND	1.37	1.34	1.36	0.46	5.52	3.90	0.67	0.45	0.84	0.30	0.89	0.88	2.04	1.33
Methyl salicylate	19.31	2.57	12.24	2.49	3.46	0.99	28.84	1.85	27.79	1.42	14.98	1.98	24.75	1.82	17.99	1.82	9.75	1.88
2-Methoxycinnamaldehyde	ND	ND	5.43	5.47	2.16	0.68	0.56	0.78	ND	ND	ND	ND	11.94	1.66	5.46	1.96	0.89	0.58
Phenylalanine	91.96	12.19	ND	ND	32.23	8.55	42.99	6.11	ND	ND	14.02	0.27	53.96	4.98	ND	ND	ND	ND
Shikimic acid	21.17	12.12	8.99	4.78	7.92	3.16	6.82	1.76	5.65	0.90	10.39	1.54	21.74	12.33	24.50	12.56	33.63	2.97
Succinate	1.18	0.67	0.94	0.63	1.31	0.59	0.93	0.32	0.71	0.28	1.11	0.38	1.10	0.24	0.87	0.90	1.75	0.22
Sucrose	ND	ND	ND	ND	ND	ND	ND	ND	ND	ND	2.61	2.09	9.24	8.22	6.18	4.40	7.69	1.52
Extraction yield %	5.74	1.09	6.95	1.50	4.43	0.82	11.44	1.36	13.42	3.46	10.01	1.71	16.59	0.61	18.51	2.13	13.07	1.96

ND: not detectable because under the detection limit or in a too crowded spectral area. BC: Cinnamomum cassia buds; CC: Cinnamomum cassia bark; CZ: Cinnamomum zeylanicum bark (CZ). E: alcoholic extraction in ethanol; HE: hydroalcoholic extraction in water (pH 4.5)/ethanol 7:3; H: aqueous extraction.