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PK parameters of 55 in mice.
| Property | 10 mg/kg (po) | 1.0 mg/kg (iv) |
|---|---|---|
| t1/2 (h) | 1.02 | 1.41 |
| Cmax (ng/mL) | 340.26 | 590.87 |
| CL (mL/h/kg) | ‒ | 3764.59 |
| Vss (mL/kg) | ‒ | 2574.92 |
| AUC0−t (ng·h/mL) | 165.32 | 264.27 |
| AUC0−∞ (ng·h/mL) | 168.62 | 265.63 |
| F (%) | 6.26 | ‒ |
Not applicable.
