Table 1.
Baseline Characteristics
| All Patients (n = 80) | Treatment (n = 43) | Control (n = 37) | P Value | |
|---|---|---|---|---|
| Age, median (IQR), y | 66 (56–72) | 66 (55–72) | 65 (56–71) | .904 |
| Male | 54 (67.5) | 29 (67.4) | 25 (67.6) | .990 |
| Race | .693 | |||
| White | 30 (37.5) | 16 (37.2) | 14 (37.8) | |
| Other | 30 (37.5) | 15 (34.9) | 13 (35.1) | |
| Asian | 17 (21.3) | 8 (18.6) | 9 (24.3) | |
| African American | 3 (3.8) | 2 (4.7) | 1 (2.7) | |
| Unknown | 2 (2.5) | 2 (4.7) | 0 | |
| CCI, median (IQR) | 4 (2–6) | 4 (2–5) | 4 (2–6) | .329 |
| Medical history | ||||
| DM | 39 (48.8) | 21 (48.8) | 18 (48.6) | .987 |
| MI | 21 (26.3) | 10 (23.3) | 11 (29.7) | .688 |
| Renal disease | 15 (18.8) | 7 (16.3) | 8 (21.6) | .747 |
| Smokinga | 11 (13.8) | 6 (14) | 5 (13.5) | .955 |
| Liver disease | 10 (12.5) | 5 (11.6) | 5 (13.5) | 1 |
| Asthma | 9 (11.3) | 3 (7.0) | 6 (16.2) | .290 |
| COPD | 9 (11.3) | 4 (9.3) | 5 (13.5) | .726 |
| Cancer | 9 (11.3) | 4 (9.3) | 5 (13.5) | .726 |
| Metastatic solid malignancy | 1 (1.3) | 0 | 1 (2.7) | .462 |
| Cerebrovascular disease | 8 (10) | 4 (9.3) | 4 (10.8) | 1 |
| Pulm circ disordersb | 6 (7.5) | 1 (2.3) | 5 (13.5) | .09 |
| PVD | 5 (6.3) | 1 (2.3) | 4 (10.8) | .176 |
| CHF | 2 (2.5) | 1 (2.3) | 1 (2.7) | 1 |
| Admission to ICU from ED | 27 (33.8) | 16 (37.2) | 11 (29.7) | .640 |
| Time from admission to first CMV test, median (IQR), d | 13 (8–29) | 10 (8–22) | 20 (11–35) | .037 |
| Time from admission to CMV viremia, median (IQR), d | 27 (18–39) | 25 (18–38) | 30 (20–42) | .145 |
| Time from ICU admission to first CMV test, median (IQR), d | 22 (14–32) | 7 (1–22) | 13 (4–27) | .086 |
| Time from ICU admission to CMV viremia, median (IQR), d | 22 (14–32) | 20 (12–32) | 24 (15–32) | .478 |
| Time from MV to CMV pos (n = 70) | 19 (11–32) | 19 (10–33) n = 36 | 22 (11–31) n = 34 | .672 |
All data are expressed as No. (%) unless otherwise specified.
Abbreviations: CCI, Charlson comorbidity index; CHF, congestive heart failure; CMV, cytomegalovirus; COPD, chronic obstructive pulmonary disease; DM, diabetes mellitus; ED, emergency department; ICU, intensive care unit; IQR, interquartile range; MI, myocardial infarction; MV, mechanical ventilation; PVD, peripheral vascular disease.
a
Smoking status is unreliably documented in our computerized order entry system.
b
Pulm circ disorders includes pulmonary embolism, pulmonary heart diseases (ie, pulmonary hypertension), and diseases of pulmonary vessels.