TABLE 1.
ROC Curve Analyses for Lymphocyte Count and Subsets Associated with Referring Hospitalization Unit (NOT-ICU vs ICU) and in Survival Prediction Based on Patients Age Classes
| Variable | AUC (95% Confidence Interval) | |||
|---|---|---|---|---|
| Hospitalization Unit | Age < 40 y | 40 y < Age < 60 y | Age > 60 y | Overall |
| LYM | 0.7143 (0.31485–1.0000) | 0.7339 (0.61017–0.85760) | 0.7007 (060979–0.79153) | 0.7358 (0.67041–0.80126) |
| CD3+ T cells | 0.6871 (0.25313–1.0000) | 0.7189 (0.59572–0.84206) | 0.7425 (0.65739–0.82762) | 0.7666 (0.70496–0.82822) |
| CD4+ T cells | 0.6803 (0.23878–1.0000) | 0.7556 (0.64209–0.86916) | 0.7098 (0.62083–0.79876) | 0.7637 (0.70385–0.82352) |
| CD8+ T cells | 0.7279 (0.36817–1.0000) | 0.6034 (0.46939–0.73751) | 0.7379 (0.65531–0.82056) | 0.7363 (0.67081–0.80183) |
| NLR | 0.7958 (0.73857–0.85296) | 0.8467 (0.75735–0.93606) | 0.7466 (0.66600–0.82727) | 0.8050 (0.74953–0.86038) |
| N3R | 0.6939 (0.39524–0.99251) | 0.8325 (0.74269–0.92222) | 0.7597 (0.67991–0.83952) | 0.7950 (0.73676–0.85317) |
| N4R | 0.7007 (0.42987–0.97149) | 0.8349 (0.73976–0.93003) | 0.7443 (0.66337–0.82528) | 0.8047 (0.74708–0.86239) |
| N8R | 0.7483 (0.47900–1.0000) | 0.7365 (0.62245–0.85057) | 0.7349 (0.65215–0.81764) | 0.7581 (0.69561–0.82058) |
| Survival | ||||
| LYM | 0.734 (0.628–0.840) | |||
| CD3+ T cells | 0.866 (0.784–0.947) | |||
| CD4+ T cells | 0.831 (0.747–0.915) | |||
| CD8+ T cells | 0.821 (0.735–0.907) | |||
| NLR | 0.849 (0.754–0.943) | |||
| N3R | 0.877 (0.793–0.961) | |||
| N4R | 0.858 (0.765–0.950) | |||
| N8R | 0.826 (0.726–0.926) |
AUC, area under the curve; LYM, total lymphocytes; NLR, neutrophil-to-lymphocyte ratio.