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. 2022 Jun 8;12:893319. doi: 10.3389/fonc.2022.893319

Table 1.

Summary of MPC in 2 cases with combined APL.

Case 1 2
Solid tumor Type Adenocarcinoma of the lung Hypofractionated adenocarcinoma of the stomach
Treatment modality Surgery + chemotherapy Surgery + chemotherapy
Chemotherapy drug Pemetrexed + cisplatin, gefitinib Oxaliplatin + Tegeo, Oxaliplatin + Capecitabine
Diagnosis of APL 18 months after treatment  17 months after treatment
Diagnostic basis MICM MICM
Cytogenetic characteristics t (15;17) (q24;q21),add (18) (q23) t (15;17) (q24;q21)
Molecular characteristics PML-RARα fusion gene: positive PML-RARαS subtype (bcr-3) (+) with positive WT1 expression.
Therapeutic regimen Retinoic acid, compound Huang Dai Retinoic acid, cytarabine
APL survival time 15days 15days