Table 1.
Summary of MPC in 2 cases with combined APL.
Case | 1 | 2 | |
---|---|---|---|
Solid tumor | Type | Adenocarcinoma of the lung | Hypofractionated adenocarcinoma of the stomach |
Treatment modality | Surgery + chemotherapy | Surgery + chemotherapy | |
Chemotherapy drug | Pemetrexed + cisplatin, gefitinib | Oxaliplatin + Tegeo, Oxaliplatin + Capecitabine | |
Diagnosis of APL | 18 months after treatment | 17 months after treatment | |
Diagnostic basis | MICM | MICM | |
Cytogenetic characteristics | t (15;17) (q24;q21),add (18) (q23) | t (15;17) (q24;q21) | |
Molecular characteristics | PML-RARα fusion gene: positive | PML-RARαS subtype (bcr-3) (+) with positive WT1 expression. | |
Therapeutic regimen | Retinoic acid, compound Huang Dai | Retinoic acid, cytarabine | |
APL survival time | 15days | 15days |