TABLE 3.
Antibacterial activities against Gram negative strains and Gram positive strains and antifungal activities of Cu-MOF, Zn-MOF, and Cu/Zn hybrid MOF nanostructures.
Synthetic compound/drug | Bacteria | Fungi | |||||
---|---|---|---|---|---|---|---|
Gram negative strains | Gram positive strains | ||||||
1,399 | 1709 | 1776 | 1,633 | 5,027 | |||
Cu-MOF | MIC | 64 | 512 | 128 | 128 | 256 | |
MBC/MFC | 128 | 1,024 | 256 | 256 | 256 | ||
Zn-MOF | MIC | 128 | 1,024 | 256 | 128 | 256 | |
MBC/MFC | 256 | 2048 | 512 | 256 | 512 | ||
Cu/Zn hybrid MOF | MIC | 64 | 256 | 32 | 64 | 64 | |
MBC/MFC | 64 | 512 | 64 | 128 | 128 | ||
Drug | A | MIC | — | 8 | 16 | 8 | 32 |
MBC/MFC | — | 16 | 16 | 16 | 64 | ||
B | MIC | 8 | 4 | 1 | 2 | — | |
MBC/MFC | 16 | 8 | 2 | 4 | — |
MIC, MBC, and MFC values reported as μg/mL; MBC for bacteria and MFC for fungi; drug for bacteria A: penicillin, B: gentamicin, for fungi: A: terbinafine, B: tolnaftate.