Skip to main content
. 2022 Jun 8;13:927296. doi: 10.3389/fphar.2022.927296

FIGURE 4.

FIGURE 4

Fear learning and memory of Foxg1 HET and wild-type mice. (A) There was no genotype difference in activity levels during the baseline period (prior to the first tone). (B) There was no genotype difference in percent freezing during the baseline period. (C) Foxg1 HET mice showed an increased response to the shocks (average motion during the shocks). Effect of genotype: ***p < 0.0001. (D) Foxg1 HET mice showed reduced freezing between the two tone-shock intervals. Effect of genotype: *p < 0.05. (E) Foxg1 HET mice showed reduced freezing in the contextual fear memory test. Effect of genotype: ****p < 0.0001. (F) Across the baseline and tone periods, Foxg1 HET mice froze less than wild-type mice. Effect of genotype: ****p < 0.0001. Wild-type male mice and Foxg1 HET and wild-type female mice froze more during the tone than during the pre-tone. **p < 0.01; ****p < 0.001 pre-tone versus tone periods, Sidak tests.