Table 1.
Clinical Characteristics of lung cancer patients.
| High D-dimer (N = 52) | Low D-dimer (N = 50) | p-value | |
|---|---|---|---|
| Age (years) | 66.9 ± 2.0 | 60.5 ± 1.5 | 0.153¶ |
| Gender (M/F) | 18/34 | 15/35 | 0.675§ |
| Mutation L858R Exon 19 |
28 24 |
31 19 |
NS§ |
| TKI Iressa Tarceva Afatinib |
8 18 26 |
2 23 25 |
0.123§ |
| Performance status | 0.42 ± 0.10 | 0.27 ± 0.12 | 0.329¶ |
| Response PR+CR SD+PD |
18 34 |
38 12 |
<0.001§ |
| D-dimer level (ng/dl) | 2477.0 ± 436.6 | 312.2 ± 28.2 | 0.0006¶ |
| Fibrinogen (mg/dl) | 429.8 ± 28.7 | 329.5 ± 28.2 | 0.019¶ |
| Thrombin time (s) | 17.37 ± 0.32 | 17.9 ± 0.40 | 0.312¶ |
| Platelet count (count ×103/ml) | 245.8 ± 21.4 | 259.2 ± 14.6 | 0.66¶ |
Data are means ± SEM. §Chi-square test. ¶Unpaired t-test.