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. 2022 Jun 8;13:938813. doi: 10.3389/fphar.2022.938813

TABLE 1.

Effects of JBP485 on IMP-induced changes in body and kidney weights of rabbits.

Group Body weight (kg) Δ Weight (g) Kidney (g) Kidney/body (g/kg)
0 h 72 h
Control 2.55 ± 0.05 2.59 ± 0.05 40.67 ± 1.76 11.37 ± 0 0.29 4.38 ± 0.03
IMP 2.52 ± 0.13 2.37 ± 0.15 −153.33 ± 21.28* 14.20 ± 0.21* 6.03 ± 0.30*
JBP485 2.65 ± 0.09 2.69 ± 0.09 41.00 ± 1.53# 11.37 ± 0.18# 4.23 ± 0.12#
IMP + JBP485 2.58 ± 0.05 2.61 ± 0.05 22.67 ± 0.88*,# 11.33 ± 0.19# 4.35 ± 0.08#

Data are expressed as the mean ± SD. *p < 0.05 compared with control; # p < 0.05 compared with IMP group (n = 3).