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. 2022 Jun 8;13:865097. doi: 10.3389/fphar.2022.865097

TABLE 1.

Key transcription factors associated with critical targets.

Key transcription factors Description p value
RELA V-rel reticuloendotheliosis viral oncogene homolog A (avian) 1.33E-49
NFKB1 Nuclear factor of kappa light polypeptide gene enhancer in B cells 1 3.34E-46
JUN Jun proto-oncogene 2.28E-41
SP1 Sp1 transcription factor 2.52E-39
STAT3 Signal transducer and activator of transcription 3 (acute-phase response factor) 2.7E-33
TP53 Tumor protein p53 1.03E-26
EGR1 Early growth response 1 5.56E-23
ETS1 V-ets erythroblastosis virus E26 oncogene homolog 1 (avian) 3.68E-22
STAT1 Signal transducer and activator of transcription 1, 91 kDa 1.15E-21
BRCA1 Breast cancer 1, early onset 4.04E-21