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Model simulations of panitumumb and emibetuzumab pharmacokinetics (PK). (A) single-dose PK for panitumumab from 0.75–9 mg/kg simulated out to 14 days, (B) multi-dose PK for 6 mg/kg Q2W panitumumab simulated out to 64 days, (C) single-dose PK for emibetuzumab for 20–2000 mg doses simulated out to 14 days.
