Figure 4.

Patch-level feature interpretation in the pCR group (A–E) and non-pCR group (F–J). Patches in the correctly predicted pCR group (A) and correctly predicted non-pCR group (F). PatchPRs were categorized into six phenotype clusters based on t-SNE and the Raster Fairy method, and each grid represented an individual patch (B, G). The importance distribution of the patches in the pCR group (C) and non-pCR group (H). Darker colors represent the patches that played a more important role in pCR or non-pCR prediction. Demonstration of patch importance and the number of patches in each cluster; the size of the bubble represents the number of patches in the corresponding cluster (D, I). Representative patches of cluster 1 (E) and cluster 2 (J) and the part of the WSI from which they were selected.