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. 2021 Dec 1;12(6):2934–2949. doi: 10.1016/j.apsb.2021.11.020

Figure 3.

Figure 3

Maturation of BMDCs induced by JQ-1@PSNs-R + L. (A) Schematic illustration of the process of obtaining preparations, stimulating BMDCs and detections. (B) Percentage of mature BMDCs after stimulation. (C) Contour map of flow cytometry results of mature BMDCs. (D) After preparations stimulation, the cytokines secreted by BMDCs were tested by ELISA kits. Compared with PBS, Free JQ-1, PSNs-R and JQ-1@PSNs-R, the IL-6 and TNF-α secretion levels of JQ-1@PSNs-R + L were significantly increased. Data were mean ± SEM, n = 4 and analyzed by one-way ANOVA, ∗∗P < 0.01 and ∗∗∗∗P < 0.0001.