Supplementary Table S5.

List of Microbial Species that Are Differentially Abundant between Different Subgroup in the Cohort

Microbial Species	Base Mean	Log2 Fold Change	P-Value	Padj	Comparison Pair
Turicibacter unclassified	148.1650263	‒25.09944303	1.48E–25	2.77E–23	c2c1
Coprococcus sp ART55 1	17,348.22439	‒30	4.07E–22	3.80E–20	c2c1
Phascolarctobacterium succinatutens	16,877.86806	‒30	5.75E–20	3.58E–18	c2c1
Turicibacter sanguinis	30.89947547	‒23.71828011	1.25E–19	5.84E–18	c2c1
Coprococcus sp ART55 1	17,348.22439	‒32.10303282	4.81E–18	9.82E–16	c2c3
P. succinatutens	16,877.86806	‒27.87316104	1.19E–12	8.08E–11	c2c3
Turicibacter unclassified	148.1650263	‒20.02159204	2.65E–12	1.35E–10	c2c3
Megamonas unclassified	13,738.87404	‒10.70556321	1.26E–06	1.03E–05	c2c1
Megamonas unclassified	13,738.87404	‒12.64875264	1.93E–06	2.81E–05	c2c3
T. sanguinis	30.89947547	‒15.01564462	2.39E–06	3.25E–05	c2c3
Ruminococcaceae bacterium D16	318.9654536	‒8.1375798	0.000312498	0.003363951	c3c1
T. sanguinis	30.89947547	‒8.702635493	0.000532915	0.005417965	c3c1
Lachnospiraceae bacterium 1 1 57FAA	2,253.140867	‒6.756348377	0.000705118	0.006791396	c3c1
Streptococcus thermophilus	2,905.078536	‒4.197322843	0.002619562	0.020410751	c2c1
Prevotella copri	69,851.06368	‒4.796452699	0.003805748	0.028466996	c2c1
S. thermophilus	2,905.078536	‒5.017689601	0.002810256	0.035830762	c2c3
Bacteroides xylanisolvens	1,773.658642	3.277724558	0.005561142	0.039997442	c2c1

Abbreviation: adj, adjusted.