Table 5.
Relationship between the time interval between two ovulation induction IUI trearment cycles and clinical pregnancy after adjusting for confounding factors
Variable | Control group | B value | OR value | OR 95% CI | P value |
Time interval | |||||
Discontinuous | Continuous | −0.016 | 0.984 | 0.495 to 1.957 | 0.964 |
Male age (years) | −0.026 | 0.974 | 0.849 to 1.117 | 0.708 | |
Female age (years) | 0.016 | 1.016 | 0.876 to 1.179 | 0.831 | |
Type of infertility | |||||
Secondary infertility | Primary infertility | 1.07 | 2.917 | 1.421 to 5.988 | 0.004 |
Female BMI | 0.059 | 1.061 | 0.972 to 1.159 | 0.186 | |
Endometrial thickness (mm) | 0.196 | 1.217 | 1.056 to 1.401 | 0.006 | |
Semen volume before treatment (mL) | −0.224 | 0.799 | 0.615 to 1.039 | 0.095 | |
Sperm density before treatment (×106 /mL) | −0.004 | 0.996 | 0.987 to 1.004 | 0.318 | |
Percentage of forward motile sperm before treatment (%) | −0.005 | 0.995 | 0.97 to 1.021 | 0.73 | |
Sperm density after treatment (×106 /mL) | 0.004 | 1.004 | 0.995 to 1.013 | 0.419 | |
Percentage of forward motile sperm after treatment (%) | 0.041 | 1.042 | 0.937 to 1.157 | 0.448 | |
Duration of infertility | |||||
2–5 years | ≤2 years | 0.298 | 1.347 | 0.668 to 2.715 | 0.405 |
>5 years | ≤2 years | −0.836 | 0.433 | 0.159 to 1.185 | 0.103 |
Endometrial classification, n (%) | |||||
B | A | −0.694 | 0.5 | 0.243 to 1.026 | 0.059 |
C | A | 0.409 | 1.505 | 0.312 to 7.254 | 0.61 |
Infertility factors | |||||
Ovulation disorders | Cervical factors | 1.091 | 2.978 | 0.585 to 15.175 | 0.189 |
Unexplained infertility | Cervical factors | 0.143 | 1.153 | 0.205 to 6.475 | 0.871 |
Tubal problems | Cervical factors | 0.568 | 1.765 | 0.285 to 10.939 | 0.541 |
Male factor | Cervical factors | 1.224 | 3.4 | 0.504 to 22.941 | 0.209 |
Adjustment factors include: Female age, male age, infertility duration, infertility type, female BMI, endometrial classification, endometrial thickness, semen volume before treatment, sperm density before treatment, percentage of forward motile sperm before treatment, sperm density after treatment, percentage of forward motile sperm after treatment, infertility factors and the time interval between two ovulation induction IUI trearment cycles.
BMI, body mass index; IUI, intrauterine insemination.