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. 2022 Jun 20;12(6):e061043. doi: 10.1136/bmjopen-2022-061043

Table 5.

Relationship between the time interval between two ovulation induction IUI trearment cycles and clinical pregnancy after adjusting for confounding factors

Variable Control group B value OR value OR 95% CI P value
Time interval
 Discontinuous Continuous −0.016 0.984 0.495 to 1.957 0.964
Male age (years) −0.026 0.974 0.849 to 1.117 0.708
Female age (years) 0.016 1.016 0.876 to 1.179 0.831
Type of infertility
 Secondary infertility Primary infertility 1.07 2.917 1.421 to 5.988 0.004
Female BMI 0.059 1.061 0.972 to 1.159 0.186
Endometrial thickness (mm) 0.196 1.217 1.056 to 1.401 0.006
Semen volume before treatment (mL) −0.224 0.799 0.615 to 1.039 0.095
Sperm density before treatment (×106 /mL) −0.004 0.996 0.987 to 1.004 0.318
Percentage of forward motile sperm before treatment (%) −0.005 0.995 0.97 to 1.021 0.73
Sperm density after treatment (×106 /mL) 0.004 1.004 0.995 to 1.013 0.419
Percentage of forward motile sperm after treatment (%) 0.041 1.042 0.937 to 1.157 0.448
Duration of infertility
 2–5 years ≤2 years 0.298 1.347 0.668 to 2.715 0.405
 >5 years ≤2 years −0.836 0.433 0.159 to 1.185 0.103
Endometrial classification, n (%)
 B A −0.694 0.5 0.243 to 1.026 0.059
 C A 0.409 1.505 0.312 to 7.254 0.61
Infertility factors
 Ovulation disorders Cervical factors 1.091 2.978 0.585 to 15.175 0.189
 Unexplained infertility Cervical factors 0.143 1.153 0.205 to 6.475 0.871
 Tubal problems Cervical factors 0.568 1.765 0.285 to 10.939 0.541
 Male factor Cervical factors 1.224 3.4 0.504 to 22.941 0.209

Adjustment factors include: Female age, male age, infertility duration, infertility type, female BMI, endometrial classification, endometrial thickness, semen volume before treatment, sperm density before treatment, percentage of forward motile sperm before treatment, sperm density after treatment, percentage of forward motile sperm after treatment, infertility factors and the time interval between two ovulation induction IUI trearment cycles.

BMI, body mass index; IUI, intrauterine insemination.