Table 4.
Capture–recapture analysis of meningococcal septicaemia reported to the SDR and MRS stratified by characteristics, Catalonia 2011–2015
| Records in SDR, n | Records in MRS, n | Matched records | Calculated unreported cases | Estimated total number of cases (95% CI) |
Sensitivity SDR (%) (95% CI) |
Sensitivity MRS (%) (95% CI) |
Difference in sensitivities (%) |
P value | |
| All cases | 82 | 66 | 50 | 10 | 108 (99 to 117) | 75.9 (67.9 to 84.0) | 61.1 (51.9 to 70.3) | 14.8 | <0.001 |
| Age at notification, years | |||||||||
| <15 years | 48 | 42 | 34 | 4 | 60 (55 to 64) | 81.1 (71.1 to 91.1) | 71.0 (59.4 to 82.5) | 10.1 | 0.036 |
| ≥15 years | 34 | 23 | 16 | 8 | 49 (40 to 58) | 70.3 (57.4 to 83.1) | 47.5 (33.4 to 61.6) | 22.7 | |
| Sex | |||||||||
| Male | 43 | 27 | 22 | 5 | 53 (47 to 59) | 81.8 (71.3 to 92.2) | 51.3 (37.8 to 64.8) | 30.4 | 0.315 |
| Female | 39 | 39 | 28 | 5 | 55 (49 to 60) | 72.0 (60.0 to 83.9) | 72.0 (60.0 to 83.9) | 0.0 | |
| Year of report | |||||||||
| 2011–2013 | 43 | 34 | 22 | 11 | 66 (56 to 77) | 65.2 (53.6 to 76.7) | 51.5 (39.5 to 63.6) | 13.6 | 0.015 |
| 2014–2015 | 39 | 32 | 28 | 2 | 45 (42 to 48) | 87.6 (78.0 to 97.3) | 71.9 (58.7 to 85.1) | 15.7 | |
| Size of municipality | |||||||||
| <10 000 people | 7 | 7 | 5 | 1 | 10 (8 to 12) | 72.2 (44.0 to 100.0) | 72.2 (44.0 to 100.0) | 0.0 | 0.918 |
| ≥10 000 people | 71 | 52 | 43 | 6 | 86 (80 to 93) | 82.9 (74.9 to 90.8) | 60.7 (50.3 to 71.0) | 22.2 | |
| Country of birth | |||||||||
| Spain | 73 | 63 | 47 | 9 | 98 (90 to 106) | 74.7 (66.1 to 83.3) | 64.5 (55.0 to 74.0) | 10.2 | 0.275 |
| Other countries | 9 | 3 | 3 | 0 | 9 (9 to 9) | 100.0 (100.0 to 100.0) | 33.3 (2.5 to 64.1) | 66.7 | |
| Hospital beds, n | |||||||||
| <200 | 25 | 23 | 16 | 4 | 36 (31 to 42) | 70.0 (55.0 to 85.1) | 64.4 (48.7 to 80.1) | 5.6 | 0.831 |
| ≥200 | 56 | 43 | 34 | 6 | 71 (65 to 78) | 79.2 (69.7 to 88.7) | 60.8 (49.4 to 72.2) | 18.4 | |
| Type of reporting centre | |||||||||
| Private | 9 | 0 | 0 | 0 | 9 (9 to 9) | 100.0 (100.0 to 100.0) | 0 (0.0 to 0.0) | 100 | 0.988 |
| Public | 73 | 66 | 50 | 8 | 97 (89 to 104) | 75.9 (67.3 to 84.4) | 68.6 (59.3 to 77.9) | 7.3 | |
| Serogrup | |||||||||
| B | 66 | 51 | 43 | 4 | 78 (73 to 84) | 84.4 (76.4 to 92.4) | 65.2 (54.7 to 75.8) | 19.2 | 0.661 |
| C | 8 | 4 | 4 | 0 | 8 (8 to 8) | 100 (100 to 100) | 50.0 (15.4 to 84.7) | 50.0 |
MRS, microbiological reporting system; SDR, statutory disease reporting system.