Table 2.

Correlation between baseline serum TRAb levels and future changes in clinical characteristics

	CAS		NOSPECS		Proptosis
	Estimated change (SE)	P value	Estimated change (SE)	P value	Estimated change (SE)	P value
TSI	0.000 (0.001)	0.999	0.003 (0.001)	0.016	0.004 (0.002)	0.055
TBII	0.029 (0.010)	0.008	0.042 (0.019)	0.029	0.062 (0.030)	0.041

P values were calculated using a linear mixed model with time-dependent covariates adjusted for age, sex, smoking status, and treatment modality. Numbers in bold denote statistically significant changes.

CAS, clinical activity score; NOSPECS, no signs or symptoms, only signs, soft tissue involvement, proptosis, extraocular muscle involvement, corneal involvement, sight loss; TBII, thyroid-stimulating hormone receptor-binding inhibitory immunoglobulin; TRAb, thyroid-stimulating hormone receptor antibody; TSI, thyroid-stimulating immunoglobulin.