Table 2.
Comparison of echocardiographic variables used to assess FP
| Assessment of filling pressure variables | |||
| Variable | Elevated FP (N=422) | Normal FP (N=561) | P value |
| Mitral E velocity, cm/s (mean (SD)) | 127.16 (68.97) | 93.47 (54.89) | <0.001 |
| Mitral e' septal, cm/s (mean (SD)) | 5.49 (1.73) | 5.27 (1.66) | 0.044 |
| Mitral e' lateral, cm/s (mean (SD)) | 7.22 (2.36) | 7.06 (6.95) | 0.652 |
| e' average, cm/s (mean (SD)) | 6.39 (3.08) | 6.29 (4.56) | 0.682 |
| E/e' septal (mean (SD)) | 24.22 (8.99) | 17.51 (7.75) | <0.001 |
| E/e' lateral (mean (SD)) | 18.92 (7.76) | 13.64 (5.84) | <0.001 |
| Average E/e' ratio (mean (SD)) | 22.60 (15.44) | 16.69 (16.06) | <0.001 |
| LA volume index, mL/m2 (mean (SD)) | 49.53 (15.94) | 41.14 (18.95) | <0.001 |
| Tricuspid regurgitation velocity, cm/s (mean (SD)) | 323.63 (55.27) | 272.15 (62.71) | <0.001 |
| Mitral A velocity, cm/s (mean (SD))* | 76.84 (57.38) | 115.67 (71.24) | <0.001 |
| Mitral E/A ratio (mean (SD))* | 7.73 (63.56) | 0.74 (0.26) | 0.023 |
| Mitral deceleration time, ms (mean (SD))† | 165.24 (63.27) | 204.89 (69.93) | 0.001 |
| Isovolumetric relaxation time, ms (mean (SD))† | 48.47 (2.71) | 61.39 (2.93) | 0.002 |
*Only in patients in sinus rhythm at time of TTE, (N=798).
†Only in patients in Afib at time of TTE, (N=185).
FP, filling pressure; LA, left atrial; TTE, transthoracic echocardiogram.