Table 3.
Univariate and multivariable analysis of overall survival by Cox regression
| Variable | Univariate analysis | Multivariable analysis | ||
| HR (95% CI) | P value | HR (95% CI) | P value | |
| Dyslipidaemia | 0.718 (0.555 to 0.930) | 0.012 | 0.751 (0.577 to 0.978) | 0.034 |
| Hypertension | 0.656 (0.441 to 0.976) | 0.038 | 0.618 (0.412 to 0.926) | 0.020 |
| Diabetes mellitus | 1.410 (1.111 to 1.790) | 0.005 | 1.349 (1.060 to 1.718) | 0.015 |
| Atrial fibrillation | 1.502 (1.185 to 1.905) | 0.001 | 1.370 (1.070 to 1.754) | 0.012 |
| Prior PCI | 1.363 (1.073 to 1.729) | 0.011 | 1.359 (1.065 to 1.736) | 0.014 |
| Presence of pacemaker/defibrillator prior to TAVR | 1.497 (1.087 to 2.061) | 0.013 | 1.208 (0.867 to 1.684) | 0.264 |
| Elevated filling pressure | 1.390 (1.097 to 1.762) | 0.006 | 1.303 (1.025 to 1.657) | 0.031 |
| Age | 1.006 (0.992 to 1.020) | 0.84 | ||
| Gender | 0.869 (0.681 to 1.109) | 0.258 | ||
| Caucasian race | 1.285 (0.736 to 2.244) | 0.377 | ||
| Dialysis | 1.599 (0.915 to 2.793) | 0.099 | ||
| Prior CABG | 1.067 (0.823 to 1.382) | 0.622 | ||
| Prior valve replacement or repair | 1.29 (0.948 to 1.700) | 0.109 | ||
| LVEF<50% | 1.284 (0.983 to 1.676) | 0.066 | ||
CABG, coronary artery bypass grafting; LVEF, left ventricular ejection fraction; PCI, percutaneous coronary intervention; TAVR, transcatheter aortic valve replacement.