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. 2022 May 25;22(7):249–257. doi: 10.1016/j.bjae.2022.02.007

Table 1.

Studies evaluating stair climbing assessment. n, number of patients. ∗Mean age 73.2 yrs. 61% of patients ASA Class ≥3. Recruited individuals had a history of cardiovascular disease. †MACE defined as a composite of cardiac mortality, myocardial infarction, acute heart failure, life-threatening arrhythmia. No threshold value for RCRI reported. Mean age 64.3 yrs. Fifty-eight percent of patients ASA Class ≥3. §Includes myocardial ischaemia or infarction, congestive heart failure, new ventilator support ≥24 h, delirium, stroke, surgical site infection, renal insufficiency, unplanned intensive care admission. AUROC, area under the receiver operating characteristic curve; CI, confidence interval; MACE, major adverse cardiac events. MET, metabolic equivalent; RCRI, Revised Cardiac Risk Index.

First author, year (n) Surgical cohort Outcomes Thresholds for prediction Accuracy of prediction
Buse, 202120 (4,560) Inpatient, non-cardiac surgery∗ 30-day cardiac mortality, MACE,
30-day and 1-yr mortality
Self-reported ability to climb two flights of stairs (achieve 4 METs) Prediction of 30-day cardiac mortality and MACE:
RCRI alone: AUROC=0.67 (95% CI, 0.65–0.71)
Functional capacity plus RCRI: AUROC=0.72 (95% CI, 0.69–0.75)
Reilly, 199919 (600) Elective, major non-cardiac surgery Cardiovascular, pulmonary, neurological, infectious, miscellaneous complications§ Poor exercise tolerance defined as self-reported inability to climb two flights of stairs or walk four blocks Poor exercise tolerance:
Sensitivity=0.71
Specificity=0.47
Positive likelihood ratio=1.3 for predicting outcomes