Table 1.
Detection of HEV RNA in various samples from pigs experimentally infected with the membrane-associated quasi-enveloped eUS2 virus and the nonenveloped US2 virus
| Group | No. of pigs | Serum | Feces | Bile | CSF | Spinal cord (+)/(−)* | Brain (+)/(−) | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 0 dpi | 7 | 14 | 21 | 0 | 3 | 7 | 10 | 14 | 21 | 21 | 3 | 21 | 21 | 21 | ||
| Control | 7 | 0† | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0/0 | 0/0 |
| eUS2 | 7 | 0 | 0 | 1 | 0 | 0 | 1 | 7 | 7 | 7 | 1 | 3 | 0 | 0 | 0/0 | 1/0 |
| US2 | 7 | 0 | 2 | 5 | 3 | 0 | 7 | 7 | 7 | 7 | 7 | 6 | 0 | 1 | 1/0 | 3/2 |
*(+): positive-strand HEV RNA; (−): negative-strand HEV RNA.
†Number of HEV RNA-positive pigs at days post inoculation.