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Caspases Implicated in Ischemia
| Caspase | Paradigm | Measure | References |
|---|---|---|---|
| 1 | tMCAo pMCAo |
Dominant-negative Casp1 Casp1 null mice ac-YVAD-AFC mRNA |
180,216,217,226,242 |
| 2 | Global ischemia | Caspase-2 cleavage | 220 |
| 3 | tMCAo pMCAO |
Casp3 null mice WB clC3 ac-DEVD-AFC/WB/IHC mRNA |
180,208,221,226 |
| 6 | pMCAo | mRNA levels | 226 |
| 7 | pMCAo | mRNA levels | 226 |
| 8 | pMCAo | mRNA levels ac-IETD-AFC/WB/IHC |
180,221,226 |
| 9 | human stroke tissue tMCAo rodent tMCAo canine |
IHC C9 Release of C9 from mitochondria |
219,225,243 |
