Table 2.
Antibiotics and Antiparasitic Treatments for GI Disease in the Common Marmoset
Drug | Dose | Comments |
---|---|---|
Azithromycin/erythromycin | Day 1: 40 mg/kg PO d 2–5: 20 mg/kg PO q24h | Treatment of Campylobacter; extended treatment duration may be necessary41 |
Enrofloxacin | 5–10 mg/kg SC, PO, or IM q24h | To treat EPEC, Klebsiella, or Salmonella, severe colitis/enteritis2,41 |
Doxycycline | d 1: 5 mg/kg PO q12h d 2–14: 5 mg/kg PO q24h | Tetracycline antibiotic with immunomodulatory effects; consider 2–4 wk administration; treatment of IBD/CLE/chronic malabsorption |
Tinidazole | d 1: 150 mg/kg (62.5 mg) PO d 4: 77 mg/kg (31 mg) PO | Treatment of Giardia;114 contraindications include pregnancy and lactation; have utilized in young animals (3–4 mo); taste strongly aversive; recommend compounding to facilitate small volume administration (Wedgewood, 400 mg/mL as oil suspension with flavor); can be administered via oral gavage to non-sedated animals |
Metronidazole | 25–50 mg/kg PO q12-24 h for 10 d | Treatment of Giardia, Clostridium difficile, or dysbiosis6 |
Paromomycin | 15 mg/kg PO q12h for 28 d | Treatment for Cryptosporidium parvum42 |
CLE = chronic lymphocytic enteritis; EPEC = enteropathogenic Escherichia coli (E. coli); IBD = inflammatory bowel disease; IM = intramuscular; PO = per os; SC = subcutaneous.