Table 1:
Comparison of baseline characteristics Between Survivors and Non-survivors
| Totals (N=2400) |
Non-Survivors (N=1188) |
Survivors (N=1163) |
P value |
|
|---|---|---|---|---|
| Age in years (Median, SD) | 56.9 (43.6–66) | 60.2(48.9–67.9) | 52.9(38.4–62.9) | <0.001 |
| Age Group (years) | ||||
| 18–38 | 851(35.4%) | 44.1% | 26.9% | <0.001 |
| 39–52 | 621(25.8%) | 26.2% | 25.1% | 0.55 |
| 53–62 | 483(20.1%) | 16.3% | 23.8% | <0.001 |
| ≥63 | 445(18.5%) | 13.2% | 23.9% | <0.001 |
| Women | 37.0% | 35.6% | 37.8% | 0.26 |
| Race | ||||
| White | 1364(56.8%) | 55.7% | 57.8% | 0.005 |
| Black | 296(12.3%) | 11.4% | 12.8% | 0.29 |
| Asian | 274(11.4%) | 11.6% | 11.4% | 0.31 |
| Hispanic | 178 (7.4%) | 7.2% | 7.6% | 0.89 |
| Weight (kg) | ||||
| ≤ 65 | 936(39.0%) | 39.1% | 38.7% | 0.85 |
| 65–88 | 487(20.2%) | 18.7% | 21.9% | 0.058 |
| ≥89 | 977(40.7%) | 42.0% | 39.2% | 0.16 |
| SAVE Score Comorbidities | ||||
| Liver Dysfunction | 181(7.5%) | 9.3% | 5.6% | 0.001 |
| Chronic Renal Failure | 174(7.2%) | 8.5% | 5.8% | 0.01 |
| Congenital Heart Disorders | 97(4.0%) | 4.7% | 3.2% | 0.07 |
| Myocarditis | 135(5.6%) | 3.2% | 8.1% | <0.001 |
| VT/VF | 161(6.7%) | 6.3% | 6.7% | 0.63 |
| Post Heart/Lung Transplant * | 69(2.8%) | 2.4% | 3.4% | 0.15 |
| Need for Renal Replacement Therapy | 210(8.7%) | 10.8% | 6.4% | <0.001 |
| SAVE score (median, IQR) | 5 (2–8) | 4(1–6) | 6(3–8) | <0.001 |
| SAVE score (mean, SD) | 4.7 (±4.1) | 3.6(4.0) | 5.7(4.0) | |
| Pre-ECLS Intubation (hours) | ||||
| ≤10 | 392(16.3%) | 20.1 | 12.6 | <0.001 |
| 11–29 | 468(19.5%) | 19.1 | 19.5 | 0.84 |
| ≥30 | 1540(64.1%) | 60.6 | 67.8 | <0.001 |
| ECLS Characteristics | ||||
| Run-time (hours) | 119 (71–208) | 118(68–228) | 119.5(75–193) | 0.94 |
| Flow at 4 hrs | 4(3.3–4.5) | 4.0(3.32–4.57) | 3.95(3.26–4.50) | 0.10 |
| Flow at 24hrs | 4.0(3.3–4.6) | 4.07(3.5–4.70) | 4.0(3.23–4.56) | <0.001 |
| Mode | ||||
| Veno-Arterial (VA) | 2346 (97.7%) | 96.6% | 98.9% | <0.001 |
| Venovenous-Arterial (VVA) | 54(2.2%) | 3.3% | 1.0% | <0.001 |
ECLS = extracorporeal life support, SAVE = Survival after Veno-arterial ECMO, VT/VF = ventricular tachycardia or ventricular fibrillation
Includes patients with heart only, lung only, and dual heart/lung transplants