Figure 2.

Systemic administration of SL7207 induces immune cell infiltration and pro‐inflammatory immune response in the tumor. (A) Representative flow cytometry plots of CD45⁺ cells in tumors. Cells were gated on live, single cells. (B) Percentage of live cells that are CD45⁺ (n = at least 8 mice). (C) ELISA analysis of tumor lysates for IFN‐γ and (D) TNF‐α (n = 4 mice). Results displayed (A, C, & D) are representative of two independent experiments; results displayed (B) are from two independent experiments. Samples for cytokine analysis were stimulated with Cell Stimulation Cocktail (eBioscience). Results are displayed as mean ± SD with each point representing a single animal. Samples were analyzed using a Student's t‐test where *p < 0.05; **p < 0.01, and ***p < 0.001.