Table 3.
Hazard Ratios from Cox Regression Models with Time Since Loss of Ambulation, Muscular Dystrophy Surveillance, Tracking, and Research Network, 1982-2011
| Variable | Unadjusted Hazard Ratio (95% Confidence Interval) | Adjusted a Hazard Ratio (95% Confidence Interval) | 
|---|---|---|
| Race/Ethnicity | ||
| White, Non-Hispanic | Referent | Referent | 
| Black, Non-Hispanic | 1.68 (0.86 – 3.29) | 1.76 (0.84 – 3.67) | 
| Hispanic | 0.98 (0.63 – 1.52) | 1.03 (0.63 – 1.67) | 
| Others b | 0.81 (0.41 – 1.58) | 0.64 (0.31 – 1.31) | 
| Surveillance Site | ||
| Arizona | Referent | Referent | 
| Colorado | 1.01 (0.60 – 1.70) | 0.97 (0.56 – 1.68) | 
| Georgia | 1.45 (0.85 – 2.49) | 1.07 (0.58 – 1.98) | 
| Iowa | 1.08 (0.59 – 1.96) | 1.43 (0.73 – 2.81) | 
| Western New York c | 1.21 (0.65 – 2.25) | 1.33 (0.68 – 2.63) | 
| Age of First Signs and Symptoms | ||
| <1.5 years | Referent | Referent | 
| 1.5 - < 3.0 years | 0.79 (0.45 – 1.37) | 0.68 (0.38 – 1.22) | 
| 3.0 - <5.0 years | 1.42 (0.83 – 2.45) | 1.40 (0.80 – 2.45) | 
| 5.0+ years | 0.92 (0.53 – 1.62) | 0.82 (0.45 – 1.48) | 
| Ever Used Cardiac Medicationsd | 0.77 (0.52 – 1.16) | 1.04 (0.66 – 1.62) | 
| Ever Used Cough Assist Machine d | 0.46 (0.28 – 0.75) | 0.46 (0.26 – 0.80) | 
| Ever Had Scoliosis Surgery d | 0.60 (0.41 – 0.88) | 0.47 (0.31 – 0.72) | 
| Ever Used BiPAP Machine d,e | 0.76 (0.50 – 1.14) | 1.15 (0.71 – 1.86) | 
| Current Glucocorticoid Use d | 0.28 (0.11 – 0.69) | 0.23 (0.09 – 0.57) | 
Adjusted models were adjusted for all variables listed.
Other category includes individuals who were Asian, Native Hawaiian, Pacific Islander, Native American, Alaskan Native, of multiple races or whose race and ethnicity was not documented
Western New York surveillance site included 12 counties
Treatment variables were included as time-varying covariates in one-year increments
Bilevel positive airway pressure