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. Author manuscript; available in PMC: 2023 Jun 1.
Published in final edited form as: Neuromuscul Disord. 2022 Apr 30;32(6):468–476. doi: 10.1016/j.nmd.2022.04.008

Table 3.

Hazard Ratios from Cox Regression Models with Time Since Loss of Ambulation, Muscular Dystrophy Surveillance, Tracking, and Research Network, 1982-2011

Variable Unadjusted
Hazard Ratio
(95% Confidence Interval)
Adjusted a
Hazard Ratio
(95% Confidence Interval)
Race/Ethnicity
  White, Non-Hispanic Referent Referent
  Black, Non-Hispanic 1.68 (0.86 – 3.29) 1.76 (0.84 – 3.67)
  Hispanic 0.98 (0.63 – 1.52) 1.03 (0.63 – 1.67)
  Others b 0.81 (0.41 – 1.58) 0.64 (0.31 – 1.31)
Surveillance Site
  Arizona Referent Referent
  Colorado 1.01 (0.60 – 1.70) 0.97 (0.56 – 1.68)
  Georgia 1.45 (0.85 – 2.49) 1.07 (0.58 – 1.98)
  Iowa 1.08 (0.59 – 1.96) 1.43 (0.73 – 2.81)
  Western New York c 1.21 (0.65 – 2.25) 1.33 (0.68 – 2.63)
Age of First Signs and Symptoms
  <1.5 years Referent Referent
  1.5 - < 3.0 years 0.79 (0.45 – 1.37) 0.68 (0.38 – 1.22)
  3.0 - <5.0 years 1.42 (0.83 – 2.45) 1.40 (0.80 – 2.45)
  5.0+ years 0.92 (0.53 – 1.62) 0.82 (0.45 – 1.48)
Ever Used Cardiac Medicationsd 0.77 (0.52 – 1.16) 1.04 (0.66 – 1.62)
Ever Used Cough Assist Machine d 0.46 (0.28 – 0.75) 0.46 (0.26 – 0.80)
Ever Had Scoliosis Surgery d 0.60 (0.41 – 0.88) 0.47 (0.31 – 0.72)
Ever Used BiPAP Machine d,e 0.76 (0.50 – 1.14) 1.15 (0.71 – 1.86)
Current Glucocorticoid Use d 0.28 (0.11 – 0.69) 0.23 (0.09 – 0.57)
a

Adjusted models were adjusted for all variables listed.

b

Other category includes individuals who were Asian, Native Hawaiian, Pacific Islander, Native American, Alaskan Native, of multiple races or whose race and ethnicity was not documented

c

Western New York surveillance site included 12 counties

d

Treatment variables were included as time-varying covariates in one-year increments

e

Bilevel positive airway pressure