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Knockdown of lncRNA FR215775 affect Th2 cell function and differentiation; (a) the concentrations of IL-4 and IL-5 in sh-FR215775 group were significantly lower than those in the control group; (b, c) the proportion of Th2 cells decreased whereas the proportion of Th1 and Th17 cells increased in the cells of sh-FR215775 group; (d, e) the proportion of induced Th2 cells was significantly reduced in the sh-FR215775 group; (∗P < 0.05, ∗∗P < 0.01, ∗∗∗P < 0.001, ∗∗∗∗P < 0.0001).
