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. 2022 Jun 14;2022:7783481. doi: 10.1155/2022/7783481

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Copyright © 2022 Yue Ma et al.

This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Histopathological staining of murine nasal mucosa. Tissue sections were stained with (a) HE staining, (b) AB-PAS staining, (c) toluidine blue staining to analyze the severity of allergic inflammation. Photographs of representative nasal mucosal in each group (a–c; ×400 magnification; black arrows indicate stain positive cells). (d) Number of eosinophils. (e) Percent count of goblet cells. (f) Number of mast cells was significantly decreased in sh-FR215775 group (n = 5 per group). (A) The sh-FR215775 intervention AR group. (B) The sh-control intervention AR group. (C) The control cell intervention AR group. (D) The nonintervention AR group. (E) The blank control group. Data represent the mean ± SD (^∗P < 0.05, ^∗∗P < 0.01, ^∗∗∗P < 0.001, ^∗∗∗∗P < 0.0001).