Table 2.

Clinical course of the patients before and during COVID-19 pandemic

	Total patients before propensity score matching			Propensity score matched patients
	Before COVID-19 pandemic (n = 619)	During COVID-19 pandemic (n = 542)	p value	Before COVID-19 pandemic (n = 397)	During COVID-19 pandemic (n = 397)	p value
Organ support
Mechanical ventilator (%)	261 (45.2)	303 (55.9)	< 0.001	210 (52.9)	209 (52.6)	1.00
Continuous renal replacement therapy (%)	118 (19.1)	125 (22.5)	0.096	90 (22.7)	89 (22.4)	1.00
Extracorporeal membrane oxygenation (%)	14 (2.3)	18 (3.3)	0.286	11 (2.8)	15 (3.8)	0.551
Duration of hospitalization
ER length of stay (hours) (Mean ± SD, Median [IQR)])	8.70 ± 8.26 6.10 (4.11–9.58)	14.84 ± 13.30 10.21 (7.21–19.43)	< 0.001	10.14 ± 9.44 6.90 (4.52–11.24)	12.13 ± 9.96 9.08 (6.49–14.22)	0.004
ICU length of stay (days) (Mean ± SD, Median [IQR)])	5.6 ± 7.7 4 (2–7)	8.0 ± 9.3 5 (2–10)	< 0.001	6.6 ± 7.8 4 (2–8)	7.7 ± 9.0 5 (2–9)	0.060
Hospital length of stay (days) (Mean ± SD, Median [IQR])	15.8 ± 20.0 10 (4–19)	16.5 ± 16.7 12 (5–22)	0.044	16.7 ± 20.0 10 (4–22)	15.9 ± 16.0 11 (5–21)	0.589
Limitation of the treatment
Do-Not-Resuscitation (DNR) order (%)	111 (17.9)	141 (26.0)	0.002	87 (21.9)	102 (25.7)	0.243
Limitation of the treatment (%)*	81 (13.1)	111 (20.5)	0.001	57 (14.4)	76 (19.1)	0.087
DNR in hopeless patient (%)	38 (6.1)	38 (7.0)	0.555	32 (8.1)	26 (6.5)	0.496
ICU mortality (%)	154 (24.9)	199 (36.7)	< 0.001	121 (30.5)	141 (35.5)	0.151
Hospital mortality (%)	176 (28.4)	215 (39.7)	< 0.001	131 (33.0)	152 (38.3)	0.138

COVID, corona virus disease; ER, emergency room; SD, standard deviation; IQR, interquartile range; ICU, intensive care unit

^* The number of patient who refused intubation, renal replacement therapy, transfusion, vasoactive agent or chemotherapy