Table 1.
All (n=1313) | CD (n=464) | UC (n=484) | HC (n=365) | |||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
n | % | median (min-max) | n | % | median (min-max) | n | % | median (min-max) | n | % | median (min-max) | |
Age | ||||||||||||
at endoscopy | 1313 | - | 46 (18 – 82) | 464 | - | 34 (18 – 78) | 484 | - | 44 (20 – 82) | 365 | - | 54 (20 – 82) |
at diagnosis | 945 | - | 25 (2 – 75) | 462 | - | 24 (2 – 69) | 483 | - | 26 (6 – 75) | 0 | - | |
Gender | ||||||||||||
Male | 680 | 51.8 | - | 240 | 51.7 | - | 250 | 51.7 | - | 190 | 52.1 | - |
Female | 633 | 48.2 | - | 224 | 48.3 | - | 234 | 48.3 | - | 175 | 47.9 | - |
Metabolomics | ||||||||||||
serum
stool |
973 | 74.1 | - | 284 | 61.2 | - | 360 | 74.4 | - | 329 | 90.1 | - |
261 | 19.9 | - | 88 | 19 | - | 101 | 20.9 | - | 72 | 19.7 | - | |
Genotyping | ||||||||||||
genotyping | 1251 | 95.3 | - | 447 | 96.3 | - | 461 | 95.2 | - | 343 | 94 | - |
Ancestry | ||||||||||||
Asian | 16 | 1.3 | - | 4 | 0.9 | - | 4 | 0.9 | - | 8 | 2.3 | - |
Black | 112 | 9 | - | 21 | 4.7 | - | 20 | 4.3 | - | 71 | 20.7 | - |
Mexican | 68 | 5.4 | - | 21 | 4.7 | - | 30 | 6.5 | - | 17 | 5 | - |
Multiple | 114 | 9.1 | - | 34 | 7.6 | - | 21 | 4.6 | - | 59 | 17.2 | - |
White | 941 | 75.2 | - | 367 | 82.1 | - | 386 | 83.7 | - | 188 | 54.8 | - |
Clinical disease severity | ||||||||||||
HBI | 464 | - | 2 (0 – 27) | 464 | - | 2 (0 – 27) | 0 | - | - | |||
Inactive (0 −4) | 352 | 75.9 | 352 | 75.9 | ||||||||
Mild (5–7) | 67 | 14.4 | 67 | 14.4 | ||||||||
Moderate (8–16) | 42 | 9.1 | 42 | 9.1 | ||||||||
Severe (>16) | 3 | 0.6 | 3 | 0.6 | ||||||||
SCCAI | 484 | - | 1 (0 – 15) | 0 | - | 484 | - | 1 (0 – 15) | - | |||
Remission (0–4) | 430 | 88.8 | 430 | 88.8 | ||||||||
Active (>4) | 54 | 11.1 | 54 | 11.1 | ||||||||
SESCD | 464 | - | 3 (0 – 41) | 464 | - | 3 (0 – 41) | 0 | - | - | |||
Inactive(0–2) | 198 | 42.7 | 194 | 42.7 | ||||||||
Mild (3–6) | 133 | 28.7 | 133 | 28.7 | ||||||||
Moderate(7–15) | 92 | 19.8 | 92 | 19.8 | ||||||||
Severe (>15) | 41 | 8.8 | 41 | 8.8 | ||||||||
Mayo-endo | 482 | - | 1 (0 – 3) | 0 | - | 482 | - | 1 (0 – 3) | - | |||
Inactive (0) | 234 | 48.5 | 234 | 48.5 | ||||||||
Mild (1) | 153 | 31.7 | 153 | 31.7 | ||||||||
Moderate (2) | 64 | 16.3 | 64 | 16.3 | ||||||||
Severe (3) | 31 | 6.4 | 31 | 6.4 |