Kitching 1996.

Methods	Randomized, prospective single‐blind study
Participants	N = 60, age 12 months to 8 years, elective surgery (urogenital or plastic) general anaesthesia combined with regional anaesthesia Exclusion criteria: anaesthesia within preceding 3 months, current or chronic upper airway disease, asthma and congenital heart disease
Interventions	Type of LMA: LMA Classic Early removal ‐ The LMA was removed at twice MAC of halothane (adjusted for age) with N2O Late removal ‐ The LMA was removed in recovery room when the child was awake and could swallow
Outcomes	Laryngospasm Coughing Desaturation (< 95%) Excessive salivation requiring suction
Notes	Premedication ‐ oral diazepam 0.3 mg/kg and oral atropine 30 mcg/kg Induction ‐ halothane, oxygen and nitrous oxide, fentanyl 1 mcg/kg followed by insertion of the LMA Maintenance ‐ N2O + O2 + halothane, morphine 0.1 mg/kg intramuscular if required Anaesthesia deepened 5 minutes before anticipated end of surgery by giving twice the alveolar MAC of halothane adjusted for age with N2O in the early removal group
Risk of bias
Bias	Authors' judgement	Support for judgement
Random sequence generation (selection bias)	Low risk	"Allocated randomly, by tossing a coin, to have the LMA removed or left in situ"
Allocation concealment (selection bias)	Unclear risk	COMMENT ‐ No information on the method of allocation concealment
Blinding (performance bias and detection bias) Of outcome assessor to all outcomes	Unclear risk	"single blinded" COMMENT ‐ It is not clear who was blinded
Incomplete outcome data (attrition bias) All outcomes	Low risk	COMMENT ‐ Outcomes reported for all 60 patients randomized
Selective reporting (reporting bias)	Low risk	COMMENT ‐ Though no explicit statement, the outcomes mentioned in methodology have been reported