Samarkandi 1998.

Methods	Prospective, randomized trial
Participants	N = 165, ASA I, infants and children of both sexes aged 2 months to 13 years, scheduled for elective lower limb or perineal surgery Exclusion criteria ‐ current or chronic upper airway disease, asthma, congenital heart disease, major abdominal/thoracic/vascular surgery, at risk of aspiration
Interventions	Type of LMA: LMA Classic Early removal ‐ The LMA was removed and replaced with a Guedel airway Late removal ‐ The LMA was left in situ until patients demonstrated recovery of airway reflexes and had opened their eyes or mouths
Outcomes	Laryngeal spasm Coughing Desaturation Retching Bronchospasm Postop nausea and vomiting Excessive salivation
Notes	Premedication ‐ trimeprazine Induction ‐ halothane, N2O + O2 Maintenance ‐ isoflurane 1‐2%  and N2O 50% in O2 followed by the LMA, then caudal with 0.125% bupivacaine End of operation ‐ Patient was turned to one side breathing 100% oxygen 4 L/min
Risk of bias
Bias	Authors' judgement	Support for judgement
Random sequence generation (selection bias)	Low risk	"Assigned randomly according to random number generated by computer"
Allocation concealment (selection bias)	Unclear risk	COMMENT ‐ No description of method of allocation concealment
Blinding (performance bias and detection bias) Of outcome assessor to all outcomes	High risk	Not done
Incomplete outcome data (attrition bias) All outcomes	Low risk	COMMENT ‐ Outcomes have been reported for all 165 patients mentioned in methodology section
Selective reporting (reporting bias)	Low risk	COMMENT ‐ Though no explicit statement, the outcomes mentioned in methodology have been reported