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. 2022 May 10;150:e110. doi: 10.1017/S0950268822000814

Table 5.

OR between the presence of replicon types and AMR or ESBL-producing E. coli (n = 1047) and Salmonella (n = 816)

Bacterial strain Type of replicons OR of AMR phenotype (95% CI)
AMP CHP CIP GEN STR SMZ TET TMP COL ESBL producer
E. coli HI1 4.96 (2.0–12.4)a 2.62 (1.8–3.9)a 5.46 (3.7–8.0)a 5.0 (3.4–7.3)a 3.7 (2.4–5.7)a 4.2 (2.4–7.4)a 12.1 (3.8–38.4)a 2.56 (1.7–3.9)a 6.83 (4.6–10.1)a 2.5 (1.6–3.8)a
HI2 na na na na na na 20.34 (6.7–62.1)a 3.36 (1.3–8.7)a
I1-γ 0.52 (0.3–0.9)b 4.77 (3.2–7.0)a 2.5 (1.7–3.9)a 0.55 (0.4–0.8)b 6.33 (4.2–9.5)a
N 4.95 (1.8–13.7)a 2.78 (1.8–4.3)a 3.41 (2.3–5.1)a 2.34 (1.6–3.5)a 1.83 (1.2–2.8)a 2.8 (1.6–4.7)a 3.3 (1.6–6.9)a 2.95 (1.8–4.8)a 1.79 (1.1–2.8)a 1.82 (1.1–2.9)a
FIA 3.67 (2.2–6.3)a 2.0 (1.1–3.6)a 5.22 (2.1–13.2)a 2.61 (1.02–6.6)a 2.53 (1.3–4.8)a 0.19 (0.04–0.8)b
FIB 3.16 (1.9–5.3)a 1.62 (1.2–2.1)a 2.0 (1.5–2.7)a 1.56 (1.2–2.1)a 2.15 (1.6–3.0)a 2.82 (1.8–4.3)a 1.58 (1.2–2.1)a 2.36 (1.7–3.3)a
Y 3.37 (1.5–7.4)a 1.61 (1.1–2.4)a 1.92 (1.3–2.8)a 2.39 (1.6–3.6)a 2.17 (1.2–3.9)a 1.91 (1.3–2.9)a 1.93 (1.3–3.0)a 2.57 (1.7–4.0)a
P na 0.1 (0.01–0.7)b na na
FIC 0.28 (0.1–0.6)b
A/C na
FIIAs 0.65 (0.4–0.9)b 1.56 (1.02–2.3)a 0.51 (0.2–0.9)b
K 2.38 (1.7–3.4)a 2.39 (1.9–3.1)a 1.77 (1.3–2.4)a 1.99 (1.5–2.6)a 2.2 (1.7–2.8)a 2.38 (1.8–3.1)a 3.3 (2.4–4.6)a 2.07 (1.6–2.7)a 1.47 (1.04–2.1)a 2.0 (1.4–2.9)a
B/O na 9.47 (1.3–72.0)a 3.06 (1.1–8.5)a na
F 2.17 (1.5–3.1)a 1.87 (1.5–2.4)a 1.4 (1.1–1.9)a 2.55 (1.9–3.3)a 1.57 (1.2–2.0)a 1.59 (1.2–2.1)a 3.0 (2.1–4.2)a 2.76 (1.9–3.9)a 3.23 (2.2–4.7)a
Salmonella HI1 na 46.8 (6.2–350.8)a na 4.04 (1.7–9.7)a 0.22 (0.1–0.6)b na 11.9 (2.3–60.8)a 159.9 (52.0–491.3)a
HI2 na na na na
I1-γ na 4.5 (2.3–9.0)a na 5.8 (1.8–18.3)a
N 44.3 (5.9–332.7)a 14.4 (4.7–43.9)a 8.8 (3.3–23.2)a na na
FIB 4.8 (1.8–13.0)a na na na na
Y 0.17 (0.1–0.5)b na na na na na na
FIC 0.1 (0.02–0.7)b na na 0.2 (0.04–0.98)b 20.1 (2.1–191.6)a na
A/C na 14.8 (3.3–65.9)a na 14.96 (4.2–53.7)a na na na na 24.5 (7.5–80.0)a
FIIAs 0.15 (0.1–0.2)b 0.36 (0.2–0.6)b 0.2 (0.1–0.3)b
F 4.85 (2.0–12.0)a na na na

OR > 1, the resistance to the drug increased with the presence of corresponding replicon types.

OR < 1, the resistance to the drug decreased with the presence of corresponding replicon types.

a,bStatistically significant association (95% CI did not cross 1) between the presence of plasmids in particular Inc groups and resistant or ESBL-producing strains.

–, no statistically significant association (95% CI cross 1) between the presence of plasmids in particular Inc groups and resistant or ESBL-producing strains.

na, no OR due to the lack of the corresponding replicon types.

AMP, ampicillin; CHP, chloramphenicol; CIP, ciprofloxacin; GEN, gentamycin; STR, streptomycin; SMZ, sulphamethoxazole; TET, tetracycline; TMP, trimethoprim; COL, colistin.