Table 1. Literature Review Summary.
Study | Location | Patient population | Number of patients | Vaccine | Full or partial vaccinationa | Seroconversion rateb |
---|---|---|---|---|---|---|
Addeo et al. | US, Europe | Solid tumors, hematologic malignancies | 140 | Pfizer Moderna | Full | 94% |
Agha et al. | US | Hematologic malignancies | 67 | Pfizer Moderna | Full | 54% |
Dhakal et al. | US | SCT (autologous, allogeneic), CAR T-cell therapy | 130 | Pfizer Moderna JJJ | Full | 60% |
Easdale et al. | UK | SCT (allogeneic) | 55 | Pfizer AZ | Partial | 38% |
Goshen-Lago et al. | Israel | Solid tumors | 232 | Pfizer | Full | 86% |
Herishanu et al. | Israel | CLL | 167 | Pfizer | Full | 39.5% |
Maneikis et al. | Lithuania | Hematologic malignancies, SCT (autologous, allogeneic) | 857 | Pfizer | Full | N/Ac |
Palich et al. | France | Solid tumors | 223 | Pfizer | Full | 94% |
Roeker et al. | US | CLL | 44 | Pfizer Moderna | Full | 52% |
Thakkar et al. | US | Solid tumors, hematologic malignancies | 200 | Pfizer Moderna JJJ | Full | 94% |
Note. SCT = stem cell transplant; CAR = chimeric antigen receptor; CLL = chronic lymphocytic leukemia.
Full vaccination is defined as two doses of mRNA vaccine (Pfizer, Moderna), one dose of JJJ vaccine, or two doses of AZ vaccine. Partial vaccination is defined as one dose of Pfizer, Moderna, or AZ vaccines.
Rate of anti-spike IgG seropositivity following vaccination.
Note: This study measured antibody titers, rather than seroconversion rates.