Table 3.
The predictors of PM in HCC patients
| Variables | Univariable | Multivariable | ||
|---|---|---|---|---|
| sHR (95% CI) | P-value | sHR (95% CI) | P-value | |
| Development set | ||||
| Sex (male vs female) | 0.405(0.164–0.997) | 0.049 | 0.443(0.170–1.153) | 0.095 |
| Vascular invasion (Yes vs No) | 5.360(2.200–13.100) | < 0.001 | 2.610(0.898–7.596) | 0.078 |
| Tumor number (Multiple vs Single) | 0.712(0.209–2.430) | 0.590 | ||
| Tumor differentiation (Poor vs Moderate/well) | 1.310(0.498–3.450) | 0.580 | ||
| Capsule (Incomplete vs Complete) | 3.110(1.230–7.850) | 0.017 | 1.490(0.534–4.181) | 0.440 |
| Tumor size (cm) | 1.330(1.200–1.460) | < 0.001 | 1.240(1.045–1.481) | 0.014 |
| AFP (ng/mL) | 1.000(1.000–1.000) | 0.090 | ||
| PDW (%) | 0.798(0.706–0.901) | < 0.001 | 0.850(0.736–0.983) | 0.028 |
| Validation set | ||||
| Cirrhosis (Yes vs No) | 0.089(0.011–0.703) | 0.022 | 0.376(0.028–4.970) | 0.460 |
| Child Pugh score (B vs A) | 6.270 (1.970–19.900) | 0.001 | 2.587(0.378–17.682) | 0.330 |
| Tumor size (cm) | 1.530(1.350–1.730) | < 0.001 | 1.940(1.291–2.915) | 0.001 |
| MELD score | 0.944(0.686–1.300) | 0.720 | ||
| PALBI | 0.400(0.146–1.100) | 0.070 | ||
| AFP (ng/mL) | 1.000(1.000–1.000) | 0.630 | ||
| Haemoglobin (g/L) | 0.972(0.961–0.983) | < 0.001 | 1.046(0.988–1.107) | 0.120 |
| Platelet count (× 109/L) | 1.010(1.000–1.010) | 0.016 | 1.001(0.990–1.011) | 0.920 |
| PDW (%) | 0.764(0.645–0.904) | 0.001 | 0.523(0.304–0.898) | 0.019 |
sHR Subdistribution hazard ratio, CI Confidence interval Abbreviations: see to Table 1