Table 2.
Changes in serum and liver parameters in all groups
| Parameters | Control | Alcohol | Alcohol + L. plantarum | Alcohol + Mixed strains | p-value |
|---|---|---|---|---|---|
| ALT (IU/L) | 32.3 ± 1.9 | 46.5 ± 5.6 | 28.2 ± 6.4 | 23.0 ± 2.1 | 0.04*, 0.009**, 0.001# |
| AST (IU/L) | 152.0 ± 21.0 | 241.2 ± 11.0 | 125.5 ± 13.4 | 125.6 ± 11.8 | < 0.001*,**,# |
| TNF-α (pg/mL) | 114.1 ± 2.9 | 128.6 ± 0.9 | 115.4 ± 1.5 | 114.7 ± 1.7 | < 0.001*,**,# |
| IL-6 (pg/mL) | 267.8 ± 19.7 | 342.2 ± 15.8 | 275.3 ± 27.3 | 285.8 ± 10.6 | 0.01*, 0.02**, 0.04# |
| MDA (nmol/mg protein) | 1.34 ± 0.05 | 1.52 ± 0.04 | 1.32 ± 0.04 | 1.38 ± 0.03 | 0.005*, 0.002**, 0.03# |
| LPS (EU/mL) | 12.9 ± 4.1 | 27.8 ± 3.0 | 16.4 ± 3.4 | 18.8 ± 3.9 | 0.009*, 0.04**, 0.09# |
All parameters are presented as mean ± SD, *p-value between control and alcohol groups, **p-value between alcohol and L. plantarum groups, #p-value between alcohol and mixed strain groups