Table 2.
Univariate and multivariate analyses for overall survival of GC patients (N = 615)
| Parameters | Univariate analysis | Multivariate analysis | ||||
|---|---|---|---|---|---|---|
| HR | 95%CI | P value | HR | 95%CI | P value | |
| Gender | 1.188 | 0.86–1.64 | 0.296 | |||
| Age | 1.723 | 1.317–2.255 | < 0.001 | 1.936 | 1.467–2.555 | < 0.001 |
| ALI | 0.571 | 0.438–0.744 | < 0.001 | 0.75 | 0.567–0.992 | 0.044 |
| LPR | 11.208 | 7.541–16.658 | < 0.001 | 5.619 | 3.503–9.013 | < 0.001 |
| Tumor size | 1.154 | 1.114–1.196 | < 0.001 | 1.068 | 1.015–1.124 | 0.012 |
| Tumor location | ||||||
| proximal stomach | 1 | < 0.001 | 0.444 | |||
| distal stomach | 0.684 | 0.504–0.929 | 0.015 | 0.255 | ||
| full stomach | 1.393 | 0.952–2.037 | 0.088 | 0.302 | ||
| Histology | 0.792 | 0.591–1.06 | 0.117 | |||
| TNM stage | ||||||
| I | 1 | 1 | < 0.001 | |||
| II | 2.16 | 1.068–4.37 | 0.032 | 2.843 | 1.323–6.107 | 0.007 |
| III | 7.277 | 4.364–12.134 | < 0.001 | 7.626 | 3.937–14.774 | < 0.001 |
| Chemotherapy | 2.432 | 1.769–3.344 | < 0.001 | 0.455 | 0.305–0.68 | < 0.001 |
HR Hazard ratio, CI Confidence interval, ALI Advanced lung cancer inflammation index, LPR Lymph node positive rate on biopsy, TNM Tumor-node-metastasis. ALI was grouped according to cutoff value (39.77) obtained from ROC curve. The reference of gender, age, ALI, tumor location, histology and TNM stage was male, age < 65 years, low ALI, proximal stomach, undifferentiated and TNM stage I, respectively. LPR was analyzed as a continuous variable in univariate or multivariate analysis