Table 3.
Univariate and multivariate analyses for disease-free survival of GC patients (N = 615)
| Parameters | Univariate analysis | Multivariate analysis | ||||
|---|---|---|---|---|---|---|
| HR | 95%CI | P value | HR | 95%CI | P value | |
| Gender | 1.207 | 0.886-1.645 | 0.232 | |||
| Age | 1.693 | 1.308–2.19 | < 0.001 | 1.912 | 1.466–2.493 | < 0.001 |
| ALI | 0.562 | 0.436–0.724 | < 0.001 | 0.736 | 0.564–0.961 | 0.024 |
| LPR | 10.666 | 7.281–15.625 | < 0.001 | 5.431 | 3.45–8.55 | < 0.001 |
| Tumor size | 1.152 | 1.113–1.193 | < 0.001 | 1.069 | 1.017–1.123 | 0.008 |
| Tumor location | ||||||
| proximal stomach | 1 | < 0.001 | 0.424 | |||
| distal stomach | 0.68 | 0.508–0.91 | 0.009 | 0.215 | ||
| full stomach | 1.364 | 0.947–1.966 | 0.096 | 0.346 | ||
| Histology | 0.814 | 0.617-1.073 | 0.143 | |||
| TNM stage | ||||||
| I | 1 | < 0.001 | 1 | < 0.001 | ||
| II | 1.969 | 1.031–3.76 | 0.04 | 2.52 | 1.251–5.076 | 0.01 |
| III | 6.411 | 4.046–10.159 | < 0.001 | 6.358 | 3.471–11.648 | < 0.001 |
| Chemotherapy | 2.383 | 1.762–3.222 | < 0.001 | 0.479 | 0.325–0.705 | < 0.001 |
HR Hazard ratio, CI Confidence interval, ALI Advanced lung cancer inflammation index, LPR Lymph node positive rate on biopsy, TNM Tumor-node-metastasis. ALI was grouped according to cutoff value (39.77) obtained from ROC curve. The reference of gender, age, ALI, tumor location, histology and TNM stage was male, age < 65 years, low ALI, proximal stomach, undifferentiated and TNM stage I, respectively. LPR was analyzed as a continuous variable in univariate or multivariate analysis