TABLE 2.
The top 20 differentially expressed mRNAs in human villi during spontaneous abortion in the first trimester.
| Gene name | Log2(FC) | Regulation | Location | Strand | P-value |
|---|---|---|---|---|---|
| LILRB4 | 6.994372489 | up | chr19:54643889-54670359 | + | 2.56E-05 |
| KRT6A | 6.408677648 | up | chr12:52487174-52493257 | − | 0.000353 |
| TMEM176B | 6.402794137 | up | chr7:150791285-150801360 | − | 0.000225 |
| TMEM176A | 6.289546685 | up | chr7:150800403-150805120 | + | 0.000221 |
| WNT10A | 6.231355116 | up | chr2:218880363-218899581 | + | 0.000217 |
| CTD-2020K17.3 | 6.217088894 | up | chr17:45238028-45241734 | − | 0.000581 |
| CXCL10 | 6.158743623 | up | chr4:76021117-76023497 | − | 0.000178 |
| TNC | 5.941216251 | up | chr9:115019578-115118257 | − | 1.42E-05 |
| CD300E | 5.778269717 | up | chr17:74609887-74623738 | − | 2.10E-06 |
| CXCL9 | 5.640406283 | up | chr4:76001275-76007488 | − | 0.000375 |
| HBE1 | −13.27930895 | down | chr11:5268345-5505617 | − | 1.55E-06 |
| HBZ | −9.7258281 | down | chr16:152687-154503 | + | 1.59E-05 |
| SLC4A1 | −8.109924704 | down | chr17:44248385-44268141 | − | 3.30E-05 |
| SPTB | −7.906942374 | down | chr14:64746283-64879883 | − | 0.000189 |
| COX4I2 | −7.653108088 | down | chr20:31637888-31645006 | + | 0.000574 |
| LINC02484 | −4.950756206 | down | chr4:34120894-34269747 | − | 7.19E-10 |
| ADAMTS18 | −4.478881307 | down | chr16:77247813-77435114 | − | 0.000323 |
| RAPGEF4 | −4.44120067 | down | chr2:172735274-173052893 | + | 6.25E-10 |
| GOLGA2P7 | −4.061744557 | down | chr15:84199311-84230136 | − | 0.000712 |
| AGTR1 | −3.91772292 | down | chr3:148697784-148743008 | + | 4.73E-05 |