In vitro pharmacokinetic parameters of compound 5m.

Parameters	5m
SGF stability (% drug remaining, 2 h)	87.55 ± 0.51
SIF stability (% drug remaining, 2 h)	85.47 ± 1.12
Plasma stability (% drug remaining, 2 h)	88.69 ± 0.59
Microsomal stability (% drug remaining, 1 h)	86.77 ± 1.49
K (h−1)	0.14 ± 0.02
Half-life (h)	5.07 ± 0.72
Intrinsic clearance (μL min−1 mg−1)	4.61 ± 0.65