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. 2021 Jun 17;118(7):1713–1727. doi: 10.1093/cvr/cvab208

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© The Author(s) 2021. Published by Oxford University Press on behalf of the European Society of Cardiology.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.

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Effects of ABT-263 on peripheral blood counts and overview of effects of senolysis on atherosclerosis. (A–F) Total red blood cell (RBC) and white blood cell (WBC) counts and differential WBC and platelet counts in experimental mice at baseline and end of study after control treatment or with ABT-263. Data are means (SD), n = 12–15, Student’s t-test between baseline and end for each group. (G and H) Schematic of predicted effects of GCV treatment on experimental mice and observed or predicted consequences (G), or of ABT-263 on atherosclerosis and peripheral blood counts (H).