Table 2.
Adjusted odds of membership to cluster 2 and cluster 3 (95% CI) from the k-means clustering analysis based on demographic, behavioral, dietary, reproductive, and personal care product use correlates for women from SELF (N= 751).a,b,c
Cluster 2 | Cluster 3 | |
---|---|---|
| ||
Demographic | ||
Age, 1-year increase | 0.97 (0.91, 1.03) | 1.04 (0.99, 1.12) |
Marital Status | ||
Never married | Ref | Ref |
Currently married | 0.57 (0.36, 0.91) | 0.74 (0.44, 1.24) |
Previously married | 0.94 (0.54, 1.62) | 0.76 (0.40, 1.44) |
Education | ||
HS degree/GED | Ref | Ref |
Some college/Associate’s/Technical school | 0.92 (0.55, 1.54) | 1.34 (0.72, 2.49) |
Bachelor’s/Master’s/PhD | 0.76 (0.38, 1.51) | 1.12 (0.50, 2.47) |
Income | ||
<$20,000/year | Ref | Ref |
$20–50,000/year | 1.25 (0.78, 2.00) | 1.43 (0.84, 2.45) |
>$50,000/year | 1.40 (0.71, 2.76) | 1.63 (0.78, 3.39) |
Employment | ||
Not employed | Ref | Ref |
Employed <30 hours/week | 1.38 (0.76, 2.50) | 2.16 (1.09, 4.27) |
Employed ≥30 hours/week | 1.12 (0.72, 1.74) | 1.78 (1.07, 2.98) |
Behavioral/Anthropometric | ||
BMI (kg/m2), 1-unit increase | 1.01 (0.99, 1.03) | 1.03 (1.01, 1.05) |
Smoking | ||
Non-smoker | Ref | Ref |
Former smoker | 0.81 (0.41, 1.59) | 1.02 (0.47, 2.23) |
Current smoker <10 cigarettes/day | 1.63 (0.88, 3.00) | 2.25 (1.11, 4.55) |
Current smoker ≥10 cigarettes/day | 1.56 (0.64, 3.82) | 1.26 (0.42, 3.80) |
Alcohol use | ||
Non-drinker | Ref | Ref |
Moderate consumption | 0.86 (0.56, 1.34) | 0.92 (0.56, 1.53) |
Heavy consumption | 0.71 (0.41, 1.23) | 0.71 (0.38, 1.34) |
Dietary | ||
Number of daily servings of meat, fish, poultry, beans and eggs | 1.00 (0.92, 1.09) | 0.97 (0.88, 1.08) |
Number of daily servings of milk, yogurt and cheese | 0.81 (0.64, 1.04) | 0.96 (0.73, 1.26) |
Drank water from a plastic bottle in past 24-hr | ||
No | Ref | Ref |
Yes | 0.80 (0.54, 1.20) | 0.65 (0.42, 1.02) |
Ate food from a can in past 24-hr | ||
No | Ref | Ref |
Yes | 1.13 (0.75, 1.71) | 1.14 (0.72, 1.81) |
Reproductive | ||
Age at menarche (years) | ||
≤10 | 1.22 (0.70, 2.14) | 1.10 (0.57, 2.11) |
11 | 1.20 (0.71,2.02) | 1.04 (0.57, 1.90) |
12 | Ref | Ref |
13 | 0.92 (0.53, 1.61) | 1.07 (0.57, 2.01) |
≥14 | 1.08 (0.61, 1.93) | 1.95 (1.04, 3.67) |
Parity | ||
Nulliparous | Ref | Ref |
1 | 1.45 (0.88, 2.40) | 1.07 (0.61, 1.87) |
2 | 1.26 (0.70, 2.27) | 0.78 (0.39, 1.53) |
≥3 | 1.12 (0.60, 2.07) | 0.77 (0.37, 1.57) |
Ever use oral contraceptives | ||
No | Ref | Ref |
Yes | 1.27 (0.84, 1.94) | 0.87 (0.54, 1.40) |
Ever use progestin-only injectable | ||
No | Ref | Ref |
Yes | 0.87 (0.59, 1.30) | 0.78 (0.49, 1.22) |
Hormonal contraceptive use at baseline | ||
No | Ref | Ref |
Yes | 1.06 (0.70, 1.61) | 1.23 (0.77, 1.97) |
Current use of vaginal ring | ||
No | Ref | Ref |
Yes | 1.43 (0.76, 2.68) | 2.42 (1.28, 4.59) |
Used condoms in past 24-hr | ||
No | Ref | Ref |
Yes | 4.91 (1.61, 15.01) | 2.21 (0.60, 8.22) |
Personal care product use | ||
Used perfume in past 24-hr | ||
No | Ref | Ref |
Yes | 0.82 (0.55, 1.21) | 0.88 (0.56, 1.37) |
Used lotion before bed in past 24-hr | ||
No | Ref | Ref |
Yes | 1.01 (0.68, 1.48) | 0.93 (0.60, 1.45) |
Used make-up in past 24-hr | ||
No | Ref | Ref |
Yes | 1.12 (0.73, 1.72) | 1.11 (0.68, 1.81) |
Used nail polish in past 24-hr | ||
No | Ref | Ref |
Yes | 2.44 (1.22, 4.87) | 2.26 (1.06, 4.84) |
Used vaginal douche in past 24-hr | ||
No | Ref | Ref |
Yes | 0.80 (0.23, 2.80) | 1.11 (0.28, 4.42) |
Used vaginal powder in past 24-hr | ||
No | Ref | Ref |
Yes | 1.20 (0.68, 2.15) | 1.62 (0.87, 3.03) |
Used vaginal deodorant in past 24-hr | ||
No | Ref | Ref |
Yes | 1.60 (0.82, 3.13) | 2.38 (1.16, 4.89) |
Frequency of sunscreen use at baseline | ||
Never/hardly ever | Ref | Ref |
Sometimes | 1.30 (0.75, 2.25) | 1.20 (0.65, 2.21) |
Often | 3.38 (1.20, 9.55) | 3.20 (1.05, 9.79) |
Always/nearly always | 0.69 (0.31, 1.55) | 1.55 (0.68, 3.53) |
Cluster 1 N= 232, cluster 2 N= 318, cluster 3 N= 201
Cluster 1 is the reference cluster.
Cluster1 was characterized by the lowest biomarker concentrations, except for BPS. Cluster 2 was characterized by the highest concentrations of the parabens, two phenols (BPF and triclosan), metabolites of low molecular weight phthalates, and one metabolite of high molecular weight phthalates (MBzP). Cluster 3 was characterized by the highest concentrations for metabolites of high molecular weight phthalates (except MBzP), triclocarban, and most phenols.