TABLE 1.
Clinical scoring scale for HSV-infected mice
Score | Description of score by type |
||
---|---|---|---|
Lesion | Eye | Neurological | |
0 | Lesion free | Symptom free | Symptom free |
1 | Small area of broken skin <0.5 cm | Pus around edges | Hunched posture, normal movement |
2 | Area of broken skin 0.5–1 cm | Pus and squint | Hunched posture, slow movement |
3 | Bleeding, scabbing, or pustules | Closed | Hunched posture, labored breathing and/or hind-leg paralysis |
4 | Broken skin >1 cm with multiple pustules or scabbing | Scab formation | Hunched, ruffled fur, little to no movement |
5 | Severe scabbing or bleeding with pustules | Severe scabbing | Moribund or dead |