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. 2022 May 23;96(12):e00475-22. doi: 10.1128/jvi.00475-22

TABLE 1.

Clinical scoring scale for HSV-infected mice

Score Description of score by type
Lesion Eye Neurological
0 Lesion free Symptom free Symptom free
1 Small area of broken skin <0.5 cm Pus around edges Hunched posture, normal movement
2 Area of broken skin 0.5–1 cm Pus and squint Hunched posture, slow movement
3 Bleeding, scabbing, or pustules Closed Hunched posture, labored breathing and/or hind-leg paralysis
4 Broken skin >1 cm with multiple pustules or scabbing Scab formation Hunched, ruffled fur, little to no movement
5 Severe scabbing or bleeding with pustules Severe scabbing Moribund or dead